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Introduction to Cialis
Cialis is a brand-name prescription medication used to treat erectile dysfunction (ED) and an enlarged prostate. It was originally developed by GlaxoSmithKline and approved by the FDA in 2003 to treat ED under the brand name Cialis.
Cialis was developed as a daily medication for ED, offering a prolonged duration of action compared to other ED drugs like sildenafil (Viagra). It can be taken as a lower regular dose or a higher as-needed dose. This flexibility enables more spontaneous sexual activity compared to other on-demand ED pills.
Mechanism of Action
The mechanism of action of Cialis is similar to other PDE5 inhibitor drugs like Viagra (sildenafil) and Levitra (vardenafil). However, Cialis is different in that it has a longer duration of action. While Viagra and Levitra are effective for 4-5 hours, Cialis can work for up to 36 hours. This longer duration gives men more flexibility on when to take the medication and allows for spontaneity in sexual activity.
Cialis starts working slower than Viagra and Levitra, typically taking 30-60 minutes to reach its peak effect. Daily use can lead to quicker results due to accumulation in the body. The longer duration of Cialis is advantageous, but its slower onset should be considered compared to other ED medications.
Uses and Indications
Cialis is primarily used for the treatment of erectile dysfunction (ED) in adult men. An erection is difficult for a guy to get or sustain when they have ED. Cialis helps improve erectile function by increasing blood flow to the penis when sexually stimulated.
Cialis is also approved to treat the signs and symptoms of benign prostatic hyperplasia (BPH), which is an enlarged prostate gland. The active ingredient in Cialis, tadalafil, works to relax muscles in the prostate and bladder to improve urine flow and reduce BPH symptoms like difficulty urinating. Cialis for BPH is taken at a lower daily dose and is not for the treatment of ED.
Dosage and Administration
- Cialis is available in tablet form and comes in different dosages.10 mg is usually used as needed as the initial dose before to sexual activity. The maximum recommended dose is 20mg, with the 10mg dose proving effective for most patients.
- Cialis is a long-acting medication and can work for up to 36 hours, allowing for flexibility in sexual activity. The onset of action is usually 30-60 minutes after taking Cialis. Food does not affect absorption or onset of action.
- Cialis can be taken with or without food. For convenience, many men take it with meals. However, taking Cialis after a high-fat meal may delay absorption by about 1 hour.
- Cialis is also available in a daily lower dose tablet for continuous use, which allows for spontaneity in sexual activity. The recommended starting dose for daily use is 2.5mg taken at the same time each day. Based on efficacy and tolerability, the dose may be increased to 5mg.
Contraindications and Warnings
Cialis should not be used by the following groups:
- Those who are taking medications with nitrates, such as nitroglycerin. The mixture may result in a hazardous decrease in blood pressure.
- Individuals with severe cardiovascular conditions, such as a recent heart attack or stroke.
- People with liver or kidney disease, as the drug is metabolized through these organs.
- Those taking HIV protease inhibitors, like ritonavir or saquinavir. Cialis can interact.
- Anyone with a known allergy or hypersensitivity to tadalafil.
Prolonged erections occurred in less than 0.1% of men taking Cialis in studies. But all patients should be aware of this potential side effect. Using the lowest effective dose can help minimize risks.
Cost and Availability
Cialis is available as both a brand-name and generic medication.
Generic Cialis known as tadalafil, became available in the United States in late 2017. It is significantly less expensive than brand-name Cialis. The cost for 30 tablets ranges from $100-$200 depending on the dosage. Insurance coverage tends to be better for generic medications. With insurance, the copay for generic Cialis is often around $20 or less per prescription. The low cost makes the generic version a more accessible option for many patients.
When prescribed Cialis, it is important to discuss insurance coverage and cost with your healthcare provider. The brand name versus generic decision can be made based on insurance coverage and what fits best within your budget. With both brand-name and generic options available, Cialis can be accessible and affordable for most patients.
Lifestyle Considerations
When taking Cialis, it’s important to consider how your lifestyle and habits may impact the drug’s effectiveness and side effects.
Exercise
Regular exercise provides significant benefits that complement Cialis therapy. Exercise improves circulation, blood vessel health, heart strength, endurance and mental wellbeing. Aim for at least 150 minutes per week of moderate exercise like brisk walking. Consult your doctor before significantly increasing exercise. Avoid strenuous activity soon after taking Cialis as exertion can raise risk of side effects. Staying active and fit supports efficacy and safety of Cialis treatment.
The Future of Cialis
Cialis is likely to remain an important treatment option for erectile dysfunction in the years to come. However, ongoing research may lead to changes in how the drug is used.
While Cialis is already widely used, these innovations suggest there is still room for improvement. Patients may have more options in the future for effectively and conveniently treating erectile dysfunction with tadalafil. However, more research is needed to determine if these new approaches are safe and effective.