Opana ER (extended-release) 5mg is a prescription medication that contains oxymorphone, an opioid analgesic used for the management of severe pain requiring long-term, around-the-clock opioid treatment and for which alternative treatment options are inadequate.

Key Points about Opana ER 5mg:

1. Indications:
   • Used for managing severe pain that requires continuous, long-term opioid treatment.
   • Not intended for use on an as-needed basis for pain that is not constant.
2. Dosage:
   • The 5mg dosage refers to the amount of oxymorphone in each extended-release tablet.
   • Must be taken exactly as prescribed by a healthcare provider to avoid risks of overdose and side effects.
3. Administration:
   • Taken orally, usually every 12 hours.
   • Tablets should be swallowed whole without breaking, chewing, or crushing, to prevent a potentially fatal dose.
4. Side Effects:
   • Common side effects: nausea, vomiting, constipation, headache, dizziness, and drowsiness.
   • Serious side effects: respiratory depression, severe hypotension, and potential for addiction, abuse, and misuse.
5. Precautions:
   • Inform your doctor about any other medications you are taking and any medical conditions, especially respiratory issues, liver disease, or a history of substance abuse.
   • Avoid alcohol and certain other medications that can interact dangerously with Opana ER.
   • Not suitable for individuals with certain medical conditions like severe asthma or breathing problems, or gastrointestinal obstruction.
6. Interactions:
   • Can interact with other medications, leading to potentially dangerous effects. Common interactions include other opioids, sedatives, tranquilizers, antidepressants, and medications affecting serotonin levels.
7. Regulations:
   • Classified as a Schedule II controlled substance in the United States, indicating a high potential for abuse and dependence.
8. Monitoring:
   • Regular monitoring by a healthcare provider is necessary to adjust dosage and to check for signs of misuse, abuse, and addiction.

Important Considerations:

• Transition from Other Opioids: If transitioning from other opioids to Opana ER, careful dosage calculation and medical supervision are essential to prevent withdrawal symptoms and ensure effective pain management.
• Discontinuation: Should not be abruptly discontinued. Tapering off under medical supervision is necessary to avoid withdrawal symptoms.

Usage Guidelines:

• Always follow the healthcare provider’s instructions.
• Do not share the medication with others, especially those with a history of substance abuse or addiction.
• Store the medication securely to prevent misuse by others.